Product details

FAQ

What's the difference between CJC-1295 with DAC and without DAC?

Both are based on the same Modified GRF 1-29 core sequence, but the DAC (Drug Affinity Complex) version has a maleimido-propionyl-Lys30 modification that allows covalent binding to serum albumin, dramatically extending plasma half-life from minutes (no-DAC) to roughly a week (DAC). The clinical/research consequence is fundamentally different pharmacokinetic profiles: the no-DAC form produces pulsatile GH release that mimics physiological secretion patterns, while the DAC form produces a sustained elevation that suppresses the natural pulse architecture. Most physiological-research workflows use the no-DAC form because it preserves natural pulse architecture; the DAC form is more common in sustained-elevation research contexts.

Why is CJC-1295 almost always combined with Ipamorelin in practice?

CJC-1295 signals through the GHRH receptor; Ipamorelin signals through the GHSR (ghrelin receptor). These are two parallel input pathways that both drive somatotroph GH release, and they synergize rather than compete, combining a GHRH-pathway agonist with a GHSR-pathway agonist produces GH-release magnitudes larger than either component alone at comparable individual doses. The standard ratio for the combined product is 1:1 by mass (most commonly 2+2 mg or 5+5 mg per vial). Peptuno supplies pre-blended co-lyophilized vials under the cjc-1295-ipamorelin SKU, which is preferred over the buyer mixing the two in solution because the analytical packet certifies the actual ratio in the released vial.

How is CJC-1295 typically reconstituted and stored after opening?

Lyophilized CJC-1295 reconstitutes cleanly in bacteriostatic water for injection at typical research and compounding concentrations. The reconstituted solution is reasonably stable when held at -20 °C as single-use aliquots, but degradation accelerates with freeze-thaw cycling, the operational guidance for the GH-axis class is to aliquot immediately into the smallest workable single-use volumes and limit thaw cycles to three or fewer. The lyophilized vial itself follows the standard 24-month re-test window at -20 °C; the COA carries a documented re-test date for buyers planning recurring orders.

Certificate of Analysis (COA)