Product details
L-Carnitine (3-hydroxy-4-trimethylammoniobutanoate) is a quaternary-ammonium small molecule that shuttles long-chain fatty acids across the inner mitochondrial membrane through the carnitine-palmitoyltransferase (CPT) system — the step that makes long-chain β-oxidation possible at all. That role places it in the mitochondrial and cellular-energetics reference set, where it is used as a characterized standard in fatty-acid-oxidation and muscle-energetics studies. It is described here as an analytical standard, not for any metabolic-support outcome.
Peptuno supplies L-Carnitine as a reference standard at ≥ 99.0% purity. Because it is a small molecule rather than a peptide, the analytical workflow is matched to its polar, zwitterionic, quaternary-ammonium chemistry: HILIC or ion-exchange HPLC for chemical purity (plain reverse-phase is ineffective without modified conditions), mass-spec confirmation at 161 Da for the molecular ion, and chiral HPLC or polarimetry to confirm the L-enantiomer, since D-carnitine is the inactive enantiomer and should be absent from reference-grade material. Residual-solvent screening completes the packet. Both lyophilized powder and pre-prepared aqueous-solution fills are available for workflows that prefer a ready solution.
Regulatory note: Peptuno supplies L-Carnitine strictly for Research Use Only; buyers are responsible for verifying ingredient eligibility in their destination market.
FAQ
- How is L-Carnitine analytically characterized as a reference standard?
- Its quaternary-ammonium, zwitterionic structure dictates the methods: HILIC or ion-exchange HPLC for chemical purity (reverse-phase is ineffective without modification), mass-spec at 161 Da for the molecular ion, and chiral HPLC or polarimetry to confirm the L-enantiomer. D-carnitine is the biologically inactive enantiomer and should not be present in reference-grade material, so the chiral check is part of the release packet rather than an optional add-on.
- Which chemical form does Peptuno supply, and how do the forms differ?
- Peptuno supplies the free-base L-Carnitine by default. Acetyl-L-Carnitine (ALCAR) adds an acetyl group at the carnitine nitrogen and crosses the blood-brain barrier more readily — the form used in cognitive and neurological reference work — while L-Carnitine L-Tartrate is a co-crystal with better solid-state stability than the hygroscopic free base. ALCAR and L-Tartrate forms are available on request; specify the form at order placement since they are not interchangeable as standards.
- Why is L-Carnitine grouped with the mitochondrial reference reagents?
- Its defining function — transporting long-chain acyl groups into the mitochondrial matrix for β-oxidation via the CPT system — is squarely a mitochondrial-energetics role, which is why it sits alongside the other electron-transport and cellular-energetics standards in the catalogue rather than in a general 'other' bucket. As with the rest of that set, it is supplied as a characterized standard for bench research, not for any in vivo metabolic claim.
Certificate of Analysis (COA)
The per-lot COA for this product will appear here.